Cisplatin medication interactions

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WebSep 15, 2024 · Cisplatin may interact with anticonvulsants, or pyridoxine ( Vitamin B6 ). Tell your doctor all medications and supplements you use. What Drugs, Substances, or Supplements Interact with Cisplatin? Cisplatin is not recommended for use during pregnancy; it may harm a fetus. Cisplatin During Pregnancy and Breastfeeding WebMar 25, 2024 · AEG-1 (astrocyte elevated gene-1) promotes drug resistance by interfering with the ubiquitination and proteasomal degradation of MDR1 (multidrug resistance gene 1), thereby enhancing drug efflux. ... cisplatin resistance; interaction. Grant support 13-CX-3, 201409-202409/the Qingdao Startup and Innovation Leader Talent Plan 81472542/the ...

Cisplatin (Platinol) - Side Effects, Interactions, Uses, Dosage ...

WebApr 14, 2024 · Huixin Tan. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study, Beijing Key Laboratory of Active Substances Discovery and Drug Ability Evaluation, Department of Drug Metabolism, Institute of Materia Medica, Chinese Academy of … WebCisplatin 203 interactions Aceclofenac Both Cisplatin and Aceclofenac can increase the risk of nephrotoxicity. Aciclovir Both Cisplatin and Aciclovir can increase the risk of … inch worm nxt

Ribosome Biogenesis Regulator 1 Homolog (RRS1) Promotes Cisplatin …

WebDrug Interactions between cisplatin and Vitamin B12. This report displays the potential drug interactions for the following 2 drugs: cisplatin. Vitamin B12(cyanocobalamin) … Web1 day ago · Combined treatment with idronoxil and cisplatin enhances tumor response in humanized mice model. ... The interaction landscape between two drugs was calculated using ZIP model (right). (G) Working model depicting the interaction of IDX/Cis and memory T-cell-mediated cytotoxicity as an anti-tumor mechanism in NPC cancer cells. inch worm mit push up

Cisplatin Injection: MedlinePlus Drug Information

Side Effects of Lasix (furosemide), Warnings, Drug Interactions

WebCisplatin may cause severe kidney problems, nerve problems, and severe nausea and vomiting. Nerve problems may occur during treatment or weeks after stopping treatment. … WebApr 19, 2024 · Anaphylactic-like reactions to PLATINOL have been reported. Facial edema, bronchoconstriction, tachycardia, and hypotension may occur within minutes of PLATINOL administration. Epinephrine, corticosteroids, and antihistamines have been effectively employed to alleviate symptoms (see WARNINGS and ADVERSE REACTIONS ). income tax rates for pensioners ukWebCisplatin Interaction with 94 drugs. Find out more in the list below: Acetyldigitoxin Acetyldigitoxin may decrease the cardiotoxic activities of Cisplatin. Aclarubicin Cisplatin may... inch worm name bands

"WebCisplatin disease interactions. There are 7 disease interactions with cisplatin which include: infections. hearing loss. myelosuppression. peripheral neuropathy. renal dysfunction. hemolytic anemia. ocular toxicity. " - Cisplatin medication interactions

Cisplatin medication interactions

Cisplatin dosing, indications, interactions, adverse effects ... - Medscape

WebJan 20, 2011 · Pharmaceutical Interactions Pharmaceutical interactions occur because of a physical or chemical incompatibility. A classic example of an unwanted pharmaceutical interaction is the inactivation of the platinum compound cisplatin by the addition of the thiol mesna (sodium 2-mercaptoethanesulfonate). WebThe information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a …

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WebFeb 26, 2024 · Common side effects may include: hearing problems; kidney problems; numbness or tingling; nausea, vomiting; or. bone marrow suppression. This is not … WebSep 1, 2024 · Cisplatin for injection can cause severe hypersensitivity reactions, including anaphylaxis and death. Manifestations have included facial edema, wheezing, …

WebJan 15, 2024 · cisplatin (Platinol-AQ) cyclophosphamide (Cytoxan, Neostar) decarbazine (DTIC-Dome) ifosfamide (Ifex) lomustine (CeeNu) mechlorethamine (Mustargen) melphalan (Alkeran) oxaliplatin (Eloxatin) … Webcisplatin A total of 410 drugs are known to interact with cisplatin . Cisplatin is in the drug class alkylating agents . Cisplatin is used to treat the following conditions: Anal Cancer …

WebCisplatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: nausea vomiting diarrhea hair loss loss in ability to taste food hiccups dry mouth, dark urine, decreased sweating, dry skin, and other signs of dehydration Some side effects can be serious. WebCisplatin Disease Interactions There are 7 disease interactions with cisplatin. Infections Hearing loss Myelosuppression Peripheral neuropathy Renal dysfunction Hemolytic …

Webkidney disease. low blood counts, like white cells, platelets, or red blood cells. tingling of the fingers or toes, or other nerve disorder. an unusual or allergic reaction to cisplatin, …

Webcisplatin in biological matrices. The ratios of cisplatin to total free (ultrafilterable) platinum in the plasma vary considerably between patients and range from 0.5 to 1.1 after a dose of 100 mg/m. 2 . Cisplatin does not undergo the instantaneous and reversible binding to plasma proteins that is characteristic of normal drug-protein binding. income tax rates for south carolinaWebSep 21, 2024 · Drug interactions of furosemide include aminoglycoside antibiotics, ethacrynic acid, aspirin, lithium, sucralfate, other antihypertensive drugs, nonsteroidal anti-inflammatory drugs ( NSAIDs ), cisplatin, cyclosporine, methotrexate, phenytoin, antibiotics, heart medications, laxatives, and steroids. inch worm nestWebTreatment of lung cancer, the most common type of carcinoma, is difficult due to disease progression at the time of diagnosis, causing a high mortality rate. 1, 32 Cisplatin (DDP), also known as cis-diaminodichloplatin, is a powerful nonspecific drug blocking the cell cycle. 33, 34 DDP can enter cells through the passive transport. inch worm memeWebApr 14, 2024 · Since HK-2-cells-generated-Abs, both by cisplatin or upon UV light exposure, can induce apoptosis in HK-2 cells, the purpose of this work was to study their metabolome and therein find the molecular features which help us to unravel the mechanisms of that phenomenon. inch worm mothWebSep 18, 2024 · Caution is necessary when administering cisplatin with any of the following medications. Most drug interactions result in cumulative and dose-dependent hematologic, renal, and neurotoxic effects. Due to cumulative myelosuppression, cisplatin should also not be used concurrently with immunosuppressive medications. [28] [29] … income tax rates for scotlandWebSep 24, 2024 · Cisplatin exerts anticancer activity via multiple mechanisms. Its most acceptable mechanism involves the formation of DNA–platinum adducts by interacting with purine bases, activating several signal transduction pathways, and silencing or activating several genes which finally leads to apoptosis. income tax rates for senior citizens 2021-22WebCisplatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: nausea vomiting diarrhea hair loss loss in ability to taste food hiccups … income tax rates for seniors